Broken Heart Syndrome
The Science of Takotsubo Cardiomyopathy
The Complete Clinical Guide to Stress-Induced Cardiomyopathy
Broken Heart Syndrome is a comprehensive evidence-based reference authored by Dr A M Thirugnanam, designed to help clinicians understand, diagnose, and manage Takotsubo cardiomyopathy, one of the most fascinating and frequently underdiagnosed cardiovascular disorders. Featuring 14 chapters and 245 pages, this book provides a modern, step-by-step approach based on current international guidelines and contemporary cardiovascular research.
Takotsubo cardiomyopathy, also known as Broken Heart Syndrome, stress cardiomyopathy, or apical ballooning syndrome, often mimics acute myocardial infarction while occurring in the absence of obstructive coronary artery disease. This practical guide explains its underlying pathophysiology, clinical presentation, diagnostic criteria, imaging characteristics, treatment strategies, and long-term prognosis.
The book covers the complete spectrum of Takotsubo syndrome, including emotional and physical triggers, catecholamine-mediated myocardial injury, ECG findings, cardiac biomarkers, echocardiography, cardiac MRI, coronary angiography, differential diagnosis, complications, acute heart failure, cardiogenic shock, arrhythmias, left ventricular outflow tract obstruction, thromboembolism, recurrence prevention, and long-term patient follow-up.
Readers will gain practical expertise in:
- Early Diagnosis
- ECG Interpretation
- Echocardiography
- Cardiac MRI
- Coronary Angiography
- Acute Heart Failure Management
- Cardiogenic Shock
- Mechanical Circulatory Support
- Arrhythmia Management
- Differential Diagnosis
- Long-Term Follow-Up
- Evidence-Based Treatment
Each chapter includes:
- Clinical Algorithms
- Diagnostic Flowcharts
- Imaging Examples
- Clinical Pearls
- Evidence-Based Recommendations
- Practical Management Strategies
- Guideline Updates
- Key Learning Points
Whether you are a cardiologist, emergency physician, internist, fellow, resident, or medical student, Broken Heart Syndrome serves as an indispensable clinical reference for understanding and managing Takotsubo cardiomyopathy with confidence.
Key Topics Covered
- Takotsubo Cardiomyopathy
- Broken Heart Syndrome
- Stress Cardiomyopathy
- Apical Ballooning Syndrome
- Pathophysiology
- Catecholamine Toxicity
- Emotional Stress
- Physical Stress
- ECG Interpretation
- Echocardiography
- Cardiac MRI
- Coronary Angiography
- Acute Heart Failure
- Cardiogenic Shock
- Left Ventricular Dysfunction
- Arrhythmias
- Thromboembolism
- Differential Diagnosis
- Long-Term Follow-Up
- Evidence-Based Management
References:
American Heart Association: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.055854
Harvard University:https://www.health.harvard.edu/heart-health/takotsubo-cardiomyopathy-broken-heart-syndrome
Recommended Books:
Heart Failure Made Simple – A Global Clinician’s Guide: https://cardiologybooks.com/shop/heart-failure-made-simple/
Quick Notes in Practical Echocardiography: https://cardiologybooks.com/shop/quick-cardiology/
Differential Diagnosis in Cardiology – 1800 Clinical Cases: https://cardiologybooks.com/shop/differential-diagnosis-in-cardiology-1800-clinical-cases/







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